Did Your Heartburn Medicine Cause Kidney Disease?

PPI’s Linked To Kidney Disease & Failure

Recent research studies identified that proton pump inhibitor medications like Nexium, Prevacid, Prilosec and others that are used to control stomach acid could actually increase patient’s risk of chronic kidney disease. Proton pump inhibitors (PPI) are one of the most commonly prescribed medications in the US, and it has been estimated that between 25% and 70% Americans use a PPI on a daily basis.


Proton pump inhibitors (PPIs) are among the most commonly used drugs worldwide, and have been linked to acute interstitial nephritis, also known as kidney disease. Chronic kidney disease (CKD) is more likely to develop in people who take proton pump inhibitors (PPIs), even if they do not first experience acute kidney injury (AKI), according to a new study.

What Are Proton Pump Inhibitors (PPIs)?

Proton pump inhibitors (PPIs) are a class of medications used in treatment of:


  • Heartburn
  • Gastric Ulcers
  • Acid Reflux
  • Gastroesophageal Reflex Disease (GERD)


Examples of these medications include:


  • Omeprazole; Prilosec and Prilosec OTC
  • Dexlansoprazole; Dexilant
  • Rabeprazole; Aciphex
  • Esomeprazole; Nexium
  • Lansoprazole; Prevacid, Prevacid 24-Hour
  • Pantoprazole; Protonix
  • Omeprazole, immediate-release type, with sodium bicarbonate; Zegerid

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Side Effects of Proton Pump Inhibitors

PPIs reduce stomach acid production by blocking an acid-producing enzyme. While stomach acid is important, when it is found in the wrong place or in too large a quantity, it can result in heartburn or ulcer development. PPIs are very commonly used to combat these and other conditions. In fact, this class of medications is among the top 10 most frequently prescribed drug classes. Billions of dollars are spent on these medications every year.

Additionally, ongoing use has been linked to:


  • Increased Risk of Heart Attack
  • Kidney Failure
  • Kidney Disease
  • Osteoporosis-related Bone Fractures
  • Increased risk of Pneumonia
  • Death

Are Proton Pump Inhibitors Overused?

Many patients overuse PPIs. While these medications are helpful in treating certain conditions, an occasional bout of slight heartburn does not require this level of treatment. An H2 blocker or antacid medicine such as Tums or Maalox is sufficient. Because of the risks associated with long-term use of PPIs, it is important to use these medications sparingly—in low doses, and for short periods of time.

Call The Mulligan Law Firm for a Free Consultation About Your PPI Injury

If you have been injured due to use of proton pump inhibitor drugs, you deserve advocacy. Request a no-obligation consultation with our legal team. We have recovered compensation for clients in a broad range of injury cases involving dangerous and defective drugs. We understand how to protect you at this time. Speak with a drug injury lawyer from our office in a free consultation. Contact The Mulligan Law Firm at 1-866-529-0001 today.

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If you or a loved one were a victim of a defective medical device or a dangerous drug side effect, start your consultation now by contacting the Mulligan Law Firm. Time is limited, so contact us today. Let us help you get the compensation you deserve.